Lionel Messi had two free-kick attempts while ex-Sevilla midfielder Ivan Rakitic narrowly missed the target from inside the area.
Champions Real Madrid were beaten at home by promoted Cadiz, while Barcelona fell to their first defeat in La Liga under new coach Ronald Koeman as they lost to Getafe.
The win took Barca to the top of the standings on 68 points although Real Madrid, on 65, will reclaim their lead due to their superior head-to-head record if they beat Real Mallorca at home on Wednesday.
Barca play their final league La Liga game of the season at Alaves on Sunday before hosting Napoli on Aug. 8 in the second leg of their Champions League last-16 tie.
Barcelona endured a frustrating evening in their La Liga season opener with a 0-0 draw in a feisty affair at Getafe.
Sevilla scrambled to the top of La Liga with a scrappy 1-0 win at home to Real Valladolid, on Sunday, moving one point clear of champions Barcelona at the summit.
Barca's fans held up a mosaic before the game reading "Infinite Iniesta". They later revealed a banner saying "Thanks for so much" in tribute to a player who came through the club's academy and spent 16 years pulling the strings in midfield, winning nine Liga titles, four Champions Leagues and six domestic Cups.
Real Madrid clinched a record-extending 34th La Liga title with one game to spare by beating Villarreal 2-1 at home on Thursday thanks to two goals from their leading scorer Karim Benzema. Real have 86 points after 37 games, seven more than deposed champions Barcelona who were beaten 2-1 at home to Osasuna.
"Both in terms of what you save on the wage bill as well as the money you make, it would've been desirable. But this is something the coaching staff have to consent to and that's not my place.
The defender later became the club's assistant coach before embarking on an eventful career as a head coach, managing Dutch sides Ajax Amsterdam, PSV Eindhoven and Feyenoord plus Premier League sides Southampton and Everton and La Liga's Valencia.
Atletico Madrid secured a hard-fought 2-1 home victory over Real Betis in La Liga on Sunday thanks to an own-goal by Rui Silva and a header by Alvaro Morata as Diego Simeone's side ended a three-game winless run in all competitions.
Barca finished the season second in the standings on 82 points, four behind champions Real Madrid who visit Leganes later on Sunday. Alaves are 16th on 39.
The club could also sell other players to in order to create a new contract for Messi, who is the top scorer in La Liga this season with 13 goals.
Real Madrid's Javier Hernandez struck twice as they came from behind to beat Celta Vigo 4-2 away and keep the pressure on Barcelona at the top of La Liga on Sunday.
A Marco Asensio-inspired Real Madrid crushed Eibar 3-0 to close the gap on La Liga leaders Barcelona to five points on Sunday, with Karim Benzema starting on the bench.
Barcelona great Xavi Hernandez has said it is his dream to coach his former side
Barcelona travel to newly-promoted Osasuna without their first choice front line.
Lionel Messi marked his record 506th appearance for Barcelona in La Liga by scoring a penalty but the Catalans could only draw
Busquets, who retired from international duty last year, has made more than 700 appearances for Barcelona and holds the record for playing in more El Clasicos than any other player with 48 appearances against Barcelona's rivals Real Madrid.
Barcelona players had their families and toddlers join in their La Liga title celebrations at the Camp Nou in Barcelona on Sunday.
Barcelona coach Pep Guardiola and leading scorer Lionel Messi described their 2011 La Liga crown as the toughest of titles after securing top spot with a 1-1 draw at Levante on Wednesday.
Barca face La Liga leaders Real Sociedad on Wednesday hoping to build on their slender 1-0 victory over Levante after suffering painful defeats by Cadiz and Juventus and making their worst start to a league season in 33 years.
Records promise to tumble again in the 2012-13 La Liga season as world powerhouses Real Madrid and Barcelona resume their duel for supremacy, threatening to cast Spain's other 18 clubs even further adrift.
The season kick backs into action with a local derby between Sevilla and Real Betis on June 11 and there will be fixtures for the following seven days, with Barca hosting Leganes on June 16
Messi agreed no-fee Barca exit clause in case of Catalan independence
Pedro scored twice as Barcelona made heavy weather of beating promoted Levante 2-1 to move five points clear at the top of La Liga on Sunday.
The Catalans have kept five clean sheets in their last six games, which bodes well for their title run in.
Lionel Messi became Barca's record appearance maker in the competition with 76 Copa matches.
It was Messi's 30th goal in 39 competitive games against Atletico
Barcelona failed to capitalise on Real Madrid dropping points against Villarreal as the La Liga champions were held to a 1-1 draw at home to Atletico Madrid on Wednesday, while talisman Lionel Messi limped off with a groin injury.
Real Madrid continued their march towards a 35th LaLiga title
Luis Suarez picked up a hamstring strain in Tuesday's Champions League match at Bayern Munich.
Messi had failed to turn up to the club's tests for COVID-19 eight days ago and been absent from all subsequent sessions ahead of the new campaign after giving the club an official notice that he wished to leave.
Neto will sign a four-year deal with Barcelona that will keep him at the club until the end of the 2022-23 season and he will replace Dutch goalkeeper Jasper Cillessen who moved the other way on Wednesday.
IMAGES from the Champions League matches played on Tuesday.
Images from the La Liga match played between FC Barcelona and Sevilla on at Camp Nou on Sunday
Barcelona have no plans to re-sign Neymar from Paris St Germain, the club's vice-president Jordi Cardoner said on Friday, knocking down media reports the La Liga champions were ready to tempt the Brazilian forward back to the Nou Camp.
Barcelona midfielder Andres Iniesta has failed to recover from a calf strain and will miss Tuesday's Champions League Group F match at APOEL Nicosia.
Barcelona rubber-stamped a decade of domestic dominance by clinching the La Liga title on Sunday
Thierry Henry was on target as Barcelona cruised to a 4-0 home win over Racing Santander on Saturday to move five points clear at the top of La Liga.
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